Mergers and Acquisitions in Orthopedics multiples dates chronological



Below is my list of key acquisitions in Orthopedics by date.


You will see the pattern that most acquired companies were startups.


Click the links to read more about each acquisition.



If I missed one, let me know…






  • Stelkast in acquired by Globus Medical for $28M


  • ⓢ Link Spine is acquired by Ceiling Spine for undisclosed
  • ⓢ Atracsys Sarl (optical system for robotics) is acquired by Smith and Nephew for undisclosed




  •  OMNI is acquired by Corin for undisclosed
  •  OrthoSpace is acquired by Stryker for $220M
  •  Osiris Therapeutics is acquired by Smith and Nephew for $660M





  • Centerix Orthopaedics acquired by Smith and Nephew for $105M


Nov 2018


Sep 2018



Aug 2018


May 2018

  •  Expanding Orthopedics is acquired by CoreLink for undisclosed
  • Corin Orthopaedics is acquired by Permira, an EU private equity group for undisclosed
  •  Medical Enterprises is acquired by DePuy Synthes for its battery powered impactor for hip broaching for undisclosed
  • Bradshaw Medical is acquired by In’Tech Medical for undisclosed


Apr 2018


  • Paragon Medical is acquired by NN for $375M cash
  • JRI Orthopaedics (UK) is acquired by AK Medical (China) for $24M


Mar 2018



Feb 2018


  •  Orthotaxy, a French software-enabled surgery startup, is acquired by J&J DePuy for undisclosed


Jan 2018



Dec 2017


  •  IMASCAP, a company with shoulder replacement pre-op planning software, is acquired by Wright Medical for $89M


Oct 2017



Sept 2017



July 2017


    • Sonoma Orthopedic Products acquired by Arthrex for undisclosed (no public announcements)
    • Medshape’s ExoShape ACL portfolio is acquired by ConMed for undisclosed


  • Thortex and Millennium Surgical acquired by Avalign Technologies for undisclosed


June 2017


  • Sentio nerve location technology for spine acquired by J&J DePuy Synthes for undisclosed.


Apr 2017


  • Spinal Elements acquired by Amendia for undisclosed
  • Technology from Tissue Regeneration Systems (3D printing tissue) is acquired by Depuy Synthes for undisclosed


Feb 2017



Jan 2017


  • Interventional Spine’s assets are acquired by J&J DePuy Synthes for undisclosed


Sept 2016


  • Ivy Sports Medicine is acquired by Stryker for undisclosed
  • Clinical Graphics, an imaging company to diagnose hip impingement, is acquired by Zimmer Biomet for undisclosed
  • Instratek’s portfolio of staple and hammertoe implants and MIS soft tissue recession instrumentation is acquired by Stryker for undisclosed


Aug 2016


  • NLT Spine acquired by SeaSpine for $53M


July 2016


  • French robotics company, Medtech with technology for MIS spine procedures, Medtech, is acquired by Zimmer Biomet for $77M
  • DFine is acquired by Merit Medical for $98M
  • Wright Medical’s Tornier line of hips/knees is acquired by Corin for $38M


June 2016


  • LDR Spine is acquired by Zimmer Biomet for $1B
  • Responsive Orthopedics acquired by Medtronic for undisclosed
  • ISTO Technologies is acquired by a private equity firm for undisclosed


May 2016



Apr 2016



Jan 2016



Dec 2015



Nov 2015


  • Blue Belt Technologies with its Navio robotics system is acquired by Smith and Nephew for $275M


Sept 2015


  • Tornier’s Salto Total Ankle Replacement portfolio acquired by Integra LifeSciences for undisclosed


July 2015



    • X-Spine acquired by Bacterin for $107M and renames it Xtant Medical



June 2015



April 2015



February 2015


  • Baxano Surgical’s VEO Lateral Access & Interbody System is acquired by ChoiceSpine after the Baxano declared bankruptcy for an undisclosed sum.
  • Branch Medical Group, a Penn manufacturer, is acquired by Globus Medical for $53M
  • German Orthopedic Manufacturer acquired by Paragon Medical for an undisclosed sum


January 2015


  • BlueOrtho, a French joint navigation company, acquired by Exactech for $9.25M


November 2014



October 2014



August 2014


  • Symmetry Surgical acquired by Tecomet for $450M


June 2014



Apr 2014



Feb 2014



Jan 2014


  • Solana Surgical, a foot & ankle startup, acquired by Wright Medical for $90M
  • OrthoPro, a foot & ankle startup, acquired by Wright Medical for $35M
  • Excelsius Surgical, robotics spine patient positioning startup, acquired by Globus Medical for undisclosed
  • Covidien’s Duraseal product line a dural sealant is acquired by Integra LifeSciences for $235M


Oct 2013


  • Pipeline Orthopedics acquired by MAKO Surgical for $2.5M
  • Biotech Intl, French Foot & Ankle co, is acquired by Wright Medical for $80M
  • Lanx is acquired by Biomet for undisclosed
  • Osiris’ culture expanded stem-cell business is acquired by Mesoblast for $100M


Sept 2013



June 2013


  • Wright Medical’s Hip and Knee business is acquired by MicroPort for $290M
  • Pioneer Surgical Technology is acquired by RTI Biologics for $130M cash
  • NORMED Medizin-Technik, a German foot/ankle, hand and wrist company, acquired by Zimmer for undisclosed


May 2013



Mar 2013



Jan 2013



Nov 2012



Oct 2012


  • Santa Clara Technology’s Titanium Expandable cage technology is acquired by Spine Wave for undisclosed


Sept 2012



Aug 2012



June 2012


  • China’s Mindray Medical International, (MR) the world’s No. 3 maker of patient monitors, expanded into a new field last month by acquiring Wuhan Dragonbio Surgical Implant for $35.5M (4.6 X annual sales)
  • Spinal USA and Precision Medical of Mississippi acquired by Precision Spine for $72M


May 2012



Apr 2012


  • DePuy’s Trauma business is acquired by Biomet for $280M


Feb 2012



Jan 2012



Dec 2011


  • Symmetry Medical acquired J&J’s Codman Surgical Instruments business for $165M
  • Synovis (soft tissue repair) acquired by Baxter for $325M


Nov 2011



Sept 2011


  • Impulse Monitoring acquired by NuVasive for $80M
  • Ascension Orthopedics acquired by Integra LifeSciences  for $65M
  • Suzhou Best acquired by Microport Orthopedics for $17M


July 2011


  • Salient Surgical acquired by Medtronic for $525M
  • PEAK Surgical acquired by  Medtronic for $120M
  • KCI acquired by private equity firm Apax Partners for $6.3B
  • Beijing Montagne Medical Device acquired by Zimmer for undisclosed
  • Arthrocare’s Parallax and Contour spine lines acquired by NeuroTherm for undisclosed
  • Robinson MedSurg acquired by Bacterin for $1M


June 2011


  • Memometal Technologies acquired by Stryker for $162M
  • Amplitude acquired by Apax France, a large joint manufacturer for $66M
  • Voyant Health acquired by  Brainlab for $10M
  • TENET Medical Engineering acquired by Smith & Nephew for undisclosed
  • Orchid Orthopedic Solutions acquired by Altor for undisclosed


May 2011


  • SeaSpine acquired by Integra Orthopaedics for $89M
  • Orthovita acquired by Stryker for $316M
  • Norian assets of Synthes acquired by Kensey Nash for $22M
  • Impliant was acquired by  Premia Spine for undisclosed
  • ProChon Biotech acquired by  Histogenics for stock


April 2011


  • Synthes acquired by Johnson & Johnson for $21.3B
  • Smith & Nephew Interventional Spine Pain Mgmt acquired by NeuroTherm for undisclosed


March 2011


  • Applied Spine Technologies was acquired by Rachiotek for undisclosed
  • NovaLign (certain IP) acquired by  FlexFix/VentureMD for undisclosed
  • Beijing Wei Rui Li Medical (majority stake) was acquired by China Kanghui for undisclosed


Feb 2011


  • Genzyme was acquired by Sanofi-aventis for $20.1B
  • NovaLign (certain intramedullary designs) acquired by Sonoma Orthopedic for undisclosed


Jan 2011



Dec 2010


  • Surgical Biologics acquired by MiMedx for undisclosed
  • Stryker’s OP-1 bone growth factor acquired by Olympus for $60M
  • Sodem Diffusion/SoPlus power tools acquired by Zimmer for undisclosed
  • Small Bone Innovations’s shoulder assets acquired by FX Solutions for undisclosed


Nov 2010



Oct 2010



Sep 2010



Aug 2010


  • Osteotech acquired by Medtronic for $123M
  • VertiFlex (certain spine assets) acquired by Exactech for undisclosed


July 2010



May 2010


  • Brighton Partners polyethylene technology was acquired by Exactech for $5.5M


April 2010


  • Eska Implants was acquired by Summit Medical for undisclosed
  • Synergetics’ Sonopet/Omni lines acquired by Stryker for $3M


March 2010



Feb 2010


  • Advanced Bio-Surfaces’ OrthoGlide ankle was acquired by Memometal Technologies for undisclosed


Dec 2009


  • Scient’X acquired by Alphatec Spine for $116M