The top 10 medical device states: Everything you need to know (Medical Design and Outsourcing)

California, Minnesota and Massachusetts dominate the U.S. medical device industry. But many other states also play a significant role in medtech.

From industry employment to venture capital investment to notable industry suppliers, read on and discover how the medical device industry’s top states compare.


#1. California

California medical device industry medtech

Medical device industry employment (2019): 72,471

Medical device industry establishments (2019): 2,131

Major medical device company headquarters (2019): 19

Medical device patents (2019): 1,764

Medical device VC investments (2019): $1.249B

Medical device VC deals (2019): 72

Best States for Business ranking (2019): 31

Despite complaints about the high costs of doing business, California is unrivaled when it comes to the size of its medical device industry — not to mention the range of innovations. From medtech employment to patent numbers to the amount of venture capital investment, California is well ahead of other states. It accounted for nearly a fourth of the U.S. medical device industry’s revenue in 2017, according to IBISWorld.

The Golden State’s medical device industry is actually made up of a number of major hubs running down the length of the state:

North Bay

The North Bay region outside San Francisco is an important medical device manufacturing hub. Two of Medtronic’s business units — Aortic and Peripheral Disease Management and Coronary and Structural Heart Disease Management — are based in Santa Rosa.

Silicon Valley

Silicon Valley includes the dominant player in robotic surgery, Sunnyvale-based Intuitive Surgical. Cancer treatment innovator Varian Medical Systems is headquartered in Palo Alto, and invisible, customized orthodontics maker Align Technology is based in San Jose.

Mobile and digital health remain hot areas for the high-tech industry, with 546 digital health and 635 wearables exhibitors at this year’s CES show in Las Vegas. Cooperation between medical device companies and consumer technology companies, including Apple and Google’s life sciences sister company Verily, is increasing as more products roll out to monitor people’s health and catch problems early.

The region is also home to Carbon, a major 3D printing innovator that is forging partnerships with medical device companies including Johnson & Johnson and BD. In Milpitas, upstart Bigfoot Biomedical has a partnership with Abbott as it seeks to create an improved automated insulin delivery system for diabetes treatment. The Fogarty Institute for medical device innovation is based in Mountain View.

(Discover more about the medical device industry in Northern California at DeviceTalks West, June 23-24, 2020.)

Orange County

Orange County exported more than $4 billion worth of life science exports in 2015 alone — about three-fourths involving medical device and diagnostic equipment shipments, according to trade group Biocom. The medtech industry in the county as of 2016 included 23,673 workers, a headcount larger than most U.S. states’ medical device workforces.

The hundreds of firms in the county include Irvine-based Edwards Lifesciences, a major player in the cardiovascular devices space, and San Clemente-based ICU Medical, provider of IV-based therapies, systems and services. Johnson & Johnson’s vision surgical business, formerly part of Abbott, is based in Santa Ana.

Besides Biocom, local industry boosters include OCTANe and the Device Alliance.

The Alfred E. Mann Foundation for Scientific Research is based nearby in Valencia, and Medtronic’s diabetes business is based in the Northridge section of Los Angeles.

San Diego

San Diego is home to a number of companies pushing the boundaries when it comes to packaging digital health with medical devices, including Dexcom and its continuous glucose monitoring systems for diabetes management and ResMed and its CPAP equipment for treating sleep-related breathing disorders. Spine technology company NuVasive is also based there.

The medical device industry in San Diego County employed 9,770 people at 211 companies as of 2016, according to Biocom.

Notables in Calif.

Freudenberg Medical (Carpinteria & Baldwin Park) boasts technical capabilities ranging from the design and manufacture of minimally invasive, catheter and handheld technology to the development and production of medical components through advanced materials and processes.

Confluent Technologies (Scottsdale, Ariz.) — which works on everthing from catheter delvery systems to Nitinol guides and frames — has locations in Fremont, Campbell and Laguna Niguel.

Green Hills Software (Santa Barbara) says its products allow for faster medical device development.

Flex (Singapore; U.S. Headquarters in San Jose) offers design, engineering, manufacturing, real-time supply chain insight and logistics services.

IDEX Health & Science (Rohnert Park) focuses on advanced optofluidic technologies.

Medical Extrusion Technologies (Murrieta) has been providing custom medical tubing extrusions for more than 20 years.

Traco Power North America (San Jose) provides customers with optimal power supply solutions.

Wright Engineered Plastics (Santa Rosa) is a San Francisco Bay Area plastic injection molder and contract manufacturer.

state.


#2. Minnesota

Medical device industry employment (2019): 30,466

Medical device industry establishments (2019): 482

Major medical device company headquarters (2019): 4

Medical device patents (2019): 701

Medical device VC investments (2019): $80M

Medical device VC deals (2019): 14

Best States for Business ranking (2019): 15

Minnesota arguably has the institutions and the talent required to provide the U.S. healthcare industry the innovation it desperately needs. The question is whether potential investors will notice the hub nicknamed “Medical Alley.”

One of the nation’s top health providers, Mayo Clinic, is based in Rochester, Minn. One of the largest health insurers in the U.S., UnitedHealth Group, is based in Minnetonka, Minn., with its Optum subsidiary seeking to combine technology, data, and expertise to improve healthcare delivery. And one of the world’s largest advanced manufacturing and medical device companies, 3M Co., is headquartered in Maplewood, Minn.

The Minnesota medical device hub’s roots go back to the middle of the 20th century, when University of Minnesota surgeons including Dr. C. Walton Lillehei pioneered open-heart surgery. Lillehei happened to meet Earl Bakken, who along with brother-in-law Palmer Hermundslie had started a business out of a garage repairing hospital equipment. Lillehei tasked Bakken with finding a replacement for the large, unreliable pacemakers then in use. Bakken and Hermundslie’s business eventually grew into Fridley, Minn.–based Medtronic — now the world’s largest medical device company.

Manny Villafaña, a Bronx native who came to the Twin Cities decades ago, started out in the 1960s working on international sales for Medtronic. But he then took a risk and founded Cardiac Pacemakers Inc., which is now part of Boston Scientific’s Guidant business. Boston Sci continues to have a large presence in the Twin Cities.

By the mid-1970s, Villafaña wanted to innovate in another area: Bileaflet mechanical heart valves. The resulting company was St. Jude Medical, which Abbott acquired for $25 billion in 2018. (Villafaña, now in his 70s, remains an active entrepreneur.)

Beyond the several well-known medical device companies with large presences in Minnesota — Medtronic, Boston Scientific, Abbott, and Smiths Medical — Minnesota boasts a vast ecosystem of contract manufacturers, device testing outfits, designers, and regulatory and product development consultants to support the industry. It employed 30,466 Minnesotans in 2019, according to the Minnesota Department of Employment & Economic Development.

The University of Minnesota has a Medical Devices Center, and the Medical Alley Association is the top industry booster in the state.

Notables in Minn.

3M (Maplewood) not only sells an array of medical and surgical supplies and drug delivery systems but is also a major supplier of medical adhesives for a variety of devices.

Ametek Engineered Medical Components (Eden Prairie) boasts design and manufacturing capabilities including custom engineered interconnects, catheter components and systems, implanted lead components, ultrasound assemblies, and precision laser machining services.

Cirtec Medical (Brooklyn Park) has more than 30 years of experience developing medical devices fabricated under 21 CFR 820 and ISO 13485 quality standards. It specializes in technologies ranging from ventricular assist to cardiac rhythm management to implantable drug delivery.

CPC (Colder Products Co.) is a St. Paul-based provider of quick disconnect couplings, fittings and connectors for plastic tubing.

Testing outfit DDL is headquartered in Eden Prairie.

Donatelle (New Brighton) specializes in complex applications where precision, tolerances and validation are critical.

Freudenberg Medical has a product development center in Minnetonka that specializes in medical balloon development and prototyping and catheter-based devices.

Heraeus Medical Components (St. Paul) draws on the global resources of its German parent company to provide materials, components, assemblies and accessory devices for active devices. Heraeus also provides interventional product assembly, components and finished sterile device expertise from design through manufacturing.

Integer, which includes the former Lake Region Medical, has a major presence.

Lowell (Brooklyn Park) manufactures complex medical devices for the orthopedic and cardiovascular markets.

Minnesota Rubber and Plastics (Plymouth) designs, develops and manufactures rubber, plastic and silicone components, assemblies and finished product.

Minnetronix (St. Paul) since 1996 has been a development, manufacturing and technology partner for medical device companies around the world.

Nortech Systems (Maple Grove) is able to provide combine wire/cable, PCBA, and a number of value-added manufacturing services in an FDA-registered facility. Nortech also has Devicix, its world-class engineering services group.

Phillips-Medisize — one of the largest medical device contract manufacturers in the world — is based over the St. Croix River in Hudson, Wis.

Protolabs is a rapidly growing digital manufacturer with a variety of fast manufacturing processes that have made medical-related products ranging from fitness trackers to a blood-clot-detecting ultrasound system to ear-cleaning headphones.

Switchback Medical (Maple Grove) provides device prototyping, development and full program management.


#3. Massachusetts

Medical device industry employment (2019): 15,342

Medical device industry establishments (2019): 303

Major medical device company headquarters (2019): 7

Medical device patents (2019): 512

Medical device VC investments (2019): $385M

Medical device VC deals (2019): 29

Best States for Business ranking (2019): 19

Massachusetts may not have the medical device industry employment levels of some states. But it still deserves to be among the top three medtech states because of its large number of major company headquarters and the hundreds of millions of public and private dollars annually spent on innovation.

The Bay State is a medical research powerhouse. Its top research hospitals are among the best in the nation: Mass General, Brigham & Women’s, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston Children’s, the University of Massachusetts Medical School, and Dana Farber. In 2018 alone, these seven institutions secured thousands of NIH awards totaling $2.89 billion — up from $2.7 billion a year before, according to a Grant Thornton report prepared for trade group MassMEDIC.

Add in $499 million in medical device venture capital and headquarters of companies including Boston Scientific, Hologic, Bruker, Haemonetics, Abiomed, Insulet and NxStage Medical, and it’s little wonder that Grant Thornton found that Massachusetts leads on PMAs and 510(k) clearances when the numbers are adjusted for the size of state GDP.

Nearly a quarter of Massachusetts’ exports involve medical devices, a larger portion than any other state, according to Grant Thornton.

Notables in Mass.

Freudenberg Medical announced in 2018 that its headquarters would be located at a new facility in Beverly. The company expects the new headquarters to open this fall. Freudenberg also has a silicone manufacturing facility in Gloucester.

BMP Medical (Sterling) produces highly precise plastic consumables used in devices and diagnostic kits.

Eagle Stainless Tube & Fabrication (Franklin) specializes in fabricated products in stainless steel, nickel alloys, aluminum and titanium — including ultra-high precision, cut-to-length, stainless steel tube & bar.

maxon (Taunton) provides precision drives for insulin pumps, prostheses, active implants and more.

Software company PTC is in Boston.

Resonetics — a laser micro manufacturer —  has a facility in Nashua, N.H.

Tecomet (Wilmington) specializes in forged, cast and machined orthopedic implants, precision surgical instruments, sterilization cases/trays and photochemical etched products.

Tegra Medical (Franklin) produces components and complete devices for surgical and interventional companies. Offerings range from prototyping to full production, and from components to finished medical devices.

Testing outfit Toxikon is in Bedford.

Viant (previously MedPlast and Integer Advanced Surgical & Orthopedics) announced in 2018 that it was moving its headquarters to Foxborough.

Design outfit Ximedica is based nearby in Providence, R.I.

Hobson & Motzer (Durham, Conn.) makes precision metal components and assemblies for advanced industries.

Custom injection molder Vaupell (Seattle) has a Hudson, N.H. location.


#4. Florida

Florida top medical device states medtech

Medical device industry employment (2019): 23,015

Medical device industry establishments (2019): 1,261

Major medical device company headquarters (2019): 1

Medical device patents (2019): 204

Medical device VC investments (2019):  $43M

Medical device VC deals (2019): 2

Best States for Business ranking (2019): 5

Florida is among the top states when it comes to the number of FDA-registered medical device manufacturing facilities, according to the public-private partnership Enterprise Florida. The majority of companies are located along the Interstate 4 corridor in Central Florida, in the Jacksonville area and in South Florida.

Biotech, pharmaceutical and medical device companies with presences in the state include Actavis, Arthrex, Bristol-Myers Squibb, Johnson & Johnson, Medtronic, Noven and Steripak.

Medtronic Surgical Technologies is based in Jacksonville, and RTI Surgical is headquartered in Alachua.

Notables in FL

MicroLumen (Oldsmar) is an international manufacturer of polyimide medical and surgical tubing.

German medical materials company Raumedic has its U.S. headquarters in Mills River, N.C.

Spectrum Plastics Group, headquartered next door in Alpharetta, Ga., develops and makes specialty medical plastic products.

Zeus, a major innovator in the medical tubing space, is headquartered to the north in Orangeburg, S.C.

Polyzen (Apex, N.C.) provides offers a wide array of material formulations and processing technologies.


#5. Indiana

Warsaw Indiana top medical device states medtech orthopedics

Medical device industry employment (2019): 20,046

Medical device industry establishments (2019): 276

Major medical device company headquarters (2019): 1

Medical device patents (2019): 143

Medical device VC investments (2019): $1.7M

Medical device VC deals (2019): 2

Best States for Business ranking (2019): 12

Warsaw, Ind. is nicknamed the “Orthopedic Capital of the World.” The orthopedic medical device manufacturing industry in Warsaw has roots going back to 1895, when Revra DePuy started the DePuy Manufacturing Co. to make fiber splints. The business today is Johnson & Johnson’s DePuy Synthes Co., which employs 18,000 people across 60 countries and generates $10 billion in annual sales. DePuy Synthes is still a presence in Warsaw; its joint reconstruction business is based there.

During the 20th century, DePuy competitors Zimmer and Biomet started in Warsaw. The two in 2015 merged into Zimmer Biomet, a $7.8 billion-a-year company.

In addition to the ortho industry giants, the industry in Warsaw supports a host of suppliers. Wilmington, Mass.–based contract manufacturer Tecomet, for example, has a location in the city to serve the orthopedic device industry.

Bloomington is the home of the privately held Cook Group, a maker of minimally invasive medical devices.

Notables in Ind.

Greenlight Guru (Indianapolis) has quality management software designed specifically for the medical device industry.


#6. Pennsylvania

Philadelphia Pennsylvania top medical device states medtech

Medical device industry employment (2019): 17,144

Medical device industry establishments (2019): 418

Major medical device company headquarters (2019): 2

Medical device patents (2019): 194

Medical device VC investments (2019): $185M

Medical device VC deals (2019): 9

Best States for Business ranking (2019): 27

Pennsylvania benefits from its proximity to major companies headquartered in New Jersey and New York. Take New Brunswick, N.J.–based Johnson & Johnson as an example. Its DePuy Synthes business has a number of operations based in West Chester, and the University of Pennsylvania in Philadelphia was the first location for Johnson & Johnson Innovation’s JPOD business incubators.

Teleflex is based in Wayne, Dentsply Sirona is run out of York, and B. Braun Melsungen’s B. Braun Medical business is headquartered in Bethlehem. TE Connectivity’s U.S. headquarters are in Berwyn.

Notables in Penn.

B. Braun’s OEM Division is an outsourcing partner for medical device and pharmaceutical companies.

Fluortek (Easton) specializes in the creation of extrusions engineered to custom requirements and unique applications.

Johnson Matthey Medical Components is in West Chester.

Regulatory & Quality Solutions, also known as R&Q (Pittsburgh), provides regulatory and quality consulting and engineering for medical device and combination product companies.

Crescent Industries (New Freedom) offers 3D printing, 2D and 3D part design and mold design models, and 3D mold fill simulation and material for a wide variety of medical, dental and surgical devices.

John Evans’ Sons (Lansdale) provides medical equipment design consisting of computer monitors in fixed and mobile applications, dental x-ray equipment articulated arms as well as medical equipment drawer closing mechanisms.

Solar Atmospheres (Souderton) offers vacuum heat-treating services for implants, guide wires, stents, surgical tools, hypodermic tubing and device assemblies


#7. Texas

Medical device industry employment (2019): 15,087

Medical device industry establishments (2019): 845

Major medical device company headquarters (2019): 4

Medical device patents (2019): 217

Medical device VC investments (2019): $53M

Medical device VC deals (2019): 9

Best States for Business ranking (2019): 2

Texas has increasingly become an attractive place for growing medical device companies to set up shop; the Lone Star State ranks high on Forbes’ Best States for Business report.

It also helps that Houston is home to the largest medical complex in the world — the Texas Medical Center. The Texas Children’s Hospital and the MD Anderson Cancer Center are among the highly regarded institutions based at the Texas Medical Center.

A host of medical device OEMs have facilities in the state.

Notables in TX

AirBorn (Georgetown) has provided connectors to defense, space and medical OEMs for 60 years.

Coastal Life Technologies (San Antonio) specializes in the assembly, packaging and sterilization of single-use surgical devices.

Emergo by UL (Austin) is a global medical device regulatory consultancy.

Integer, the largest medical device contract manufacturer in the world, is headquartered in Plano.

Millar, which provides medical device companies with sensors based on Micro-Electrical Mechanical Systems (MEMS), is based in Houston.

Seisa Medical (El Paso) boasts that it can service every stage of the product life cycle including design and development, component manufacturing and final assembly.


#8. New York

Medical device industry employment (2019): 14,825

Medical device industry establishments (2019): 728

Major medical device company headquarters (2019): 2

Medical device patents (2019): 278

Medical device VC investments (2019): $41M

Medical device VC deals (2019): 6

Best States for Business ranking (2019): 28

New York state officials have lofty goals to give Massachusetts a run for its money as a life sciences innovation hub. Four years ago, Gov. Andrew Cuomo announced a $650 million initiative to create a new, world-class life science research cluster in the state.

Major medical device companies based in New York include Henry Schein (Melville) and ConMed (Utica).

Notables in NY

Huron Tool & Cutter Grinding (East Farmingdale) focuses on the design, engineering and development of sophisticated surgical tools and instruments.

Autronic Plastics (Central Islip) is a plastic injection molding company that specializes in difficult-to-process engineering resins, metal replacement, and precision plastic components, including medical/dental housings, testing components, sleep apnea products, dental scalers, medication administration devices, pump components, dental imaging equipment, and camera lenses.

Currier Plastics provides design, blow molding, injection molding, design, prototyping and manufacturing for medical devices at its Auburn facility.

Hicksville-based Designatronics’ company Stock Drive Products/Sterling Instrument (SDP/SI) supplies precision components to the medical industry, including parts for robotically assisted surgery.

Huron Tool & Cutter Grinding (East Farmingdale) is an orthopedic and arthroscopic tool contract design and manufacturing company.

Brooklyn-based Lee Spring stocks millions of springs and can custom-make springs for the medtech industry.

Medidata (New York) — acquired in 2019 by Dassault Systèmes — creates and sells software as a service for clinical trials.

MIDI offers product research and development services to medtech companies from its Smithtown headquarters.

Precipart (Farmingdale) provides precision components, custom gears, assemblies and systems integration for a wide breadth of medical applications.

Röchling Medical’s Rochester location offers contract manufacturing, product design and mold making, accelerated tooling, and engineering division.


#9. New Jersey

New Jersey top medical device states medtech

Medical device industry employment (2019): 14,039

Medical device industry establishments (2019): 418

Major medical device company headquarters (2019): 3

Medical device patents (2019): 249

Medical device VC investments (2018): $15M

Medical device VC deals (2018): 4

Best States for Business ranking (2019): 39

New Brunswick-based Johnson & Johnson has one of the largest medical device businesses in the world. Other major medical device companies including BD, Nipro, ConvaTec and Integra Lifesciences call the Garden State home.

Notables in NJ

Micro (Somerset) is a metal tubing maker.

Custom pump manufacturer KNF Neuberger is based in Trenton.

Chicago-based MW Industries has its Servometer business in Cedar Grove.

Specialty chemical maker Evonik has a plant in Piscataway and its North American headquarters in Parsippany.

Kahle Automation has its U.S. headquarters in Morristown. The company specializes in assembly technologies for needles, syringes, tubing, IV catheters and drug-device combination products.

#10. Illinois

Medical device industry employment (2019): 13,629

Medical device industry establishments (2019): 771

Major medical device company headquarters (2019): 4

Medical device patents (2015): 147

Medical device VC investments (2019): $32M

Medical device VC deals (2019): 9

Best States for Business ranking (2019): 37

Some of the medical device industry’s largest companies — including GE HealthcareAbbottBaxter, and Hill-Rom — are based in or around Chicago.

Notables in Illinois

Eastek International (Lake Zurich) boasts customized medical machining, abilities in precision manufactured products, and more.

Flexan (Lincolnshire) specializes in custom, high-precision silicone, rubber, and thermoplastic components and devices.

MW Industries (Rosemont) has specialized products for the medical and pharmaceutical industries, including precision wire forms and metal stampings. The company offers a wide variety of spring designs, tubular components and related product assemblies.

Teleflex Medical OEM (Gurnee) has a variety of expertise: extrusions; diagnostic and interventional catheters; balloons and balloon catheters; sheath/dilator sets; specialized sutures, braids, and fibers; bioabsorbable sutures, yarns and resins; and more.


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